The Haley lab is currently interested in the application of conjugated organic molecules toward various avenues:
Formally anti-aromatic, fully conjugated indenofluorene scaffolds are being explored as potential materials for organic electronics due to their ability to easily
and reversibly accept electrons, in addition to fundamental exploration of these closed-shell antiaromatic moieties.
Conjugated aryl-ethynyl systems are being investigated for use in the sensing of various biologically/environmentally relevant phenomena, utilizing the inherent
fluorescence of such systems to selectively sense or detect the presence of certain anions or potential gradients. This project is part of a collaboration with Darren
The expertise of the Haley lab is being applied toward the synthesis and SAR studies of a family of Pt compounds related to the known pharmaceutical compound, cis-platin, for study of the interactions between platinum-based reagents and cellular constituents. The Pt assay work is performed in collaboration with the DeRose lab within the Chemistry Department here at the University of Oregon.
The research described on these web pages has been generously supported by The National Science Foundation and the National Institutes of Health, with additional contributions from the Oregon Nanosciences and Microtechnologies Institute and Oregon BEST.