Haley Lab, University of Oregon

Welcome to the Haley Lab!

Recent Lab News

April 15th, 2015
  • Congratulations to Mike and Darren for winning the 2015 UO "Research Excellence Award for Innovation and Impact" for the sensing project discoveries that led to the founding of SupraSensor Technologies.

    April 12th, 2015
  • "Gute Reise!" to Gabe Rudebusch who is visiting the Tykwinski Lab in Erlangen, Germany for the next 10 weeks.

    February 25th, 2015
  • Congrats to Blake and Chris for their "Focus Review" on aryl-ethynyl scaffolds getting the cover of Chemistry-An Asian Journal!

    Cover art
    Click to expand

    DOI: 10.1002/asia.201403212

    November 3rd, 2014
  • A shout-out to Dr. Brad Rose and Conerd Frederickson on the latest two indenofluorene papers. NOW we at last know why indenofluorenes are non-fluorescent!

    DOI: 10.1016/j.cplett.2014.10.031

    and

    DOI: 10.1021/jo502009p



     
     
     
  • The Haley lab is currently interested in the application of conjugated organic molecules toward various avenues:

  • Formally anti-aromatic, fully conjugated indenofluorene scaffolds are being explored as potential materials for organic electronics due to their ability to easily and reversibly accept electrons, in addition to fundamental exploration of these closed-shell antiaromatic moieties.

  • Conjugated aryl-ethynyl systems are being investigated for use in the sensing of various biologically/environmentally relevant phenomena, utilizing the inherent fluorescence of such systems to selectively sense or detect the presence of certain anions or potential gradients. This project is part of a collaboration with Darren Johnson.

  • The synthetic expertise of the Haley lab is being applied toward the synthesis and SAR studies of a family of compounds related to the known pharmaceutical compound, pentamidine, for treatment and study of myotonic dystrophy. The assay work is performed by another lab within the Institute of Molecular Biology here at the University of Oregon, as a collaboration with Andy Berglund.